- Is the violence and the abuse the reason you ran away home?
- Are the violence and the abuse the reasons you ran away from home?
- Is the violence and the abuse the reasons you ran away home?
- Are the violence and the abuse the reason you ran away from home?
Just going from the sound of it, I would probably say #1. But from a grammatical point of view I feel compelled to go with 2. Would I be correct?