This is a question of style, and different style manuals may give different recommendations. I will be following the Chicago Manual of Style (CMOS). (CMOS).
First of all, CMOSCMOS says that abbreviations which end with a lowercase letter should contain a period after that letter (with some rare exceptions that don't apply here). Second, for Apple Inc., the period is part of the proper name, and CMOSCMOS says that respecting the form of the proper name takes precedence over whatever other rules there may be (see e.g. here). So on both counts, CMOSCMOS would frown upon removing the period after Inc.
The Chicago Manual of Style (CMOS)CMOS does allow for things like U.S.-oriented, as documented in this entry from their Q&A (here):
There is another detail here worth mentioning, coming from the fact that Apple Inc. is a compound. With compound adjectives, CMOSCMOS suggests, though doesn't exactly demand, replacing the hyphen with an en dash. In your case, that would be like this:
Here's the relevant passage from CMOSCMOS: