Yes, there should be "and x and y" to account for the last "and" at the end of the sentence.

> Her favorite types of sandwiches are ham, turkey, and peanut butter and jelly.

If you do not like that, you could rearrange the items in the list to avoid having to say "and x and y."

> Her favorite types of sandwiches are peanut butter and jelly, ham, and turkey.

It is not always incorrect to omit the last "and" in a list of items, though; there is a literary technique called [_asyndeton_](https://en.wikipedia.org/wiki/Asyndeton) that involves just that. However, it's more of a creative technique rather than something you should use in, say, a math paper.

> When she arrived at the market, she stared in awe at everything that was in stock: swords, crystals, gems, spices from faraway lands.