Unless the speaker and hearer have a shared singular conception of "efficiency and effectiveness", like as a company policy, then this is going to sound wrong to most readers, or at least those readers that stop and think about it. So it should be "those", because there are two objects being promoted, which are typically deemed to be separate.
Although who knows what the author intended, it seems like they either (a) made an antecedent error; or (b) are trying to make "efficiency and effectiveness" into a unified noun phrase, which really only works if your potential listeners share that concept.
An antecedent processing error. This is a common enough error even among native speakers, who often use the heuristic of looking to the last word referred to ("effectiveness") and inserting the corresponding pronoun form.
So as written the sentence "sounds" right on a very quick read (or writing) because one's mind does a kind of lookback function, like "was the last thing I said a plural noun or singular? ok, singular, let's say 'that' instead of 'those'".
In about 99% of sentences that heuristic works. Here it fails, and one has to really read the sentence slowly and be like "ok, these are two things that, grammatically, have to be put together to act as a plural, and so I use the plural pronoun to refer to them". That would be my suspicion as to what happened here.
Treatment as a singular noun phrase requires shared understanding of its singularity. There is, as Jason Blassford states, the possibility that the author intended for "efficiency and effectiveness" to be a singular noun phrase, like "fish and chips" or "drinking and driving". However, the difference is that "efficiency and effectiveness" do not exist most people's lexicon as a unified concept.
So while I, like most readers, would recognize either "pass me that fish and chips" (referring to the whole basket of food a single item) or "pass me those fish and chips" (referring to them is a collection of items) as grammatically valid, that is only because writer and reader share an understanding of them as a pair that can be unified.
"The thing I don't like is drinking and driving" and "The things I don't like are drinking and driving" are two sentences with two different meanings: the writer of the former is probably ok with you day-drinking at home in quarantine; but the writer of the latter probably isn't. The salient thing here is that the former only sounds grammatical because there is a widespread understanding of "drinking and driving" as a unified concept.
If one were to say, for example, "The thing I don't like is efficiency and effectiveness," in most contexts the listener is going to be like "Uh, wait, what? Which thing don't you like? Efficiency? Or effectiveness?" That sort of phrase would only work if the speaker and listener shared a unified concept of "efficiency and effectiveness", like if that were the name of a policy at a company where they both work.