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Pluripotent genes are activated in injured tissue cells and play important role in regeneration.

In the above sentence, should "play" be changed to "played" for parallel construction. Pls help.

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    Why do you think "play" should be in the past tense? Do you want to imply that these genes no longer play an important role in regeneration? Vasu, you might also find our sibling site English Language Learners is a useful source of information. Please note that English Language & Usage is a question and answer site for linguists, etymologists, and serious English language enthusiasts. – Chappo Sep 26 '18 at 9:20
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No, because they continue to play an important role after being activated. This sentence describes a sequence of actions which happen one after another, rather than two things happening in parallel.

Also, it should be play an important role.

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