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For example, we can say "important research ", "foundational research", "meaningful", "influential", "impactive", or "imperative". But those words are either far too common or too weak. What is a better choice?

I remember something like "se***m***ntic".

marked as duplicate by Edwin Ashworth single-word-requests Jul 3 '18 at 19:17

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seminal TFD

  1. highly original, influential, and important; highly original and influencing the development of future events

As in:

a seminal artist; a seminal idea, seminal (work of) research

etymology:

Figurative sense of "full of possibilities" is attested from 1630s.

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The closest word to your example I can think of is seminal, but you might also consider vital, groundbreaking, critical, preeminent, prototypical, demiurgic, or paradigmatic.

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