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Here's a sentence from a test:

To be honest, there aren't many things Serena isn't good ___.

What preposition should I use after 'good'? I think both 'at' and 'with' are possible. Can I also use 'in'?

Which would be the most natural to say for a native speaker? (The test only accepts one answer.)

closed as off-topic by Edwin Ashworth, Phil Sweet, Lawrence, NVZ, curiousdannii Sep 1 '16 at 7:00

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    While R Mac lists the prepositions 'good' often colligates with, the only one sounding natural (in terminal position) here is 'at'. – Edwin Ashworth Aug 31 '16 at 18:43
  • In everyday language that means 'combines with', which is the standard grammatical expression for denoting the adjoining of a preposition and the word it complements. – BillJ Aug 31 '16 at 19:34
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One may be good with nouns, indicating that one is proficient at use of the noun.

"Suzy is good with the cello." "Eddy is good with a paint brush." "Lauren is good with engines."

One may be good at a noun which is a gerund or when using the word "that" to refer to an activity.

"Patrick is good at [playing] baseball." "Emily is good at carving pumpkins." "Fitzgerald is good at that."

One may be good in a place--but only if the activity in question (at which one is good) is implied--or in a role (for instance, when acting).

"Jessica is good in the driver's seat." "Derek is good in the field." "Lesley is good in villain roles."

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