What is a word that would mean or can be used to describe rising against someone or something, either from a force/people/trials?
The word that works best should be "revolt":
to act in a way that shows that you do not accept the control or influence of someone or something
Also, check the following synonyms mentioned along with that definition of revolt in MW:
insurgence, insurgency, insurrection, mutiny, outbreak, rebellion, revolution, rising, uprising