"Make it into" means "make its way into."
For example, if you were waiting at the end of a very long line of people to get into a concert, I might ask you the next day: "Did you make it into the concert?"
Similarly, if you are trying to get to the post office before it closes, you might say, "I'm afraid I'm not going to make it."
So you've looked up the wrong definition. You're not making something into something, you're making it into something.
Applying this to your text, we could rewrite the sentence thus:
By its nature, a proportion of bleeding edge technology will be incorporated into the mainstream.
By its nature, a proportion of bleeding edge technology will become mainstream.
This latter rewrite, however, does change the sense somewhat, in particular, the focus.
Edit: There is persistent insistence that "make something into something" means to transform. However, that is not the correct sense for this use of the phrase "make it into."
Rather, it is the preposition "into" with the phrasal verb "make it," meaning to reach or attain. It is not necessary to use an additional preposition, but it is possible. For example, you can ask someone, did you make it?
One can make it over the bridge; one can make it to the church in time; one can make it under the limbo bar. And an idea can make it into a document.
Here's a sample of what Google returned for an exact phrase search on "make it into." I am ignoring the hit for this question itself, for one irrelevant result, and I'm only counting the first instance of Meryl Streep's Golden Globes speech; otherwise these are the results that appeared on the first two pages. I evaluate each result as to whether it represents the meaning "transform" or "attain inclusion."
- Meryl Streep quoting Carrie Fisher saying "take your broken heart, make it into art"
- 6 CRAZY HERO ABILITIES That Didn't Make It Into Overwatch - YouTube
- Is it too late for me to make it into Yale? - Quora
- The Next Craft Beer Trend: Make It Into Whiskey - Men's Journal
- ROGUE ONE Trailer Moments That Didn't Make It Into The Film | Birth ...
- New IRS data show that 71% of US taxpayers who make it into the ‘Top 400’ are there for only a single year
- Lost Scriptures: Books that Did Not Make It into the New Testament ...
- Make it into management. african-female. The corporate sector can be highly competitive. If you have been working hard and not getting the promotion you feel
- Ideas on Photography - make it into a game.
- Do Stokes, Broad & Cook make it into your top 10 of 2016? - BBC Sport
- Which Star Wars Trailer Moments Didn't Make It Into The Movie
- Can Georgia make it into the top five of recruiting classes? - ESPN Video
- 5 Facts About McDonald's That Didn't Make It Into 'The Founder' - Peta
- How can longshot teams make it into the playoffs? - NFL Videos
- Packers will pound the Lions, Redskins make it into the playoffs.
That's three points for "transform" and twelve points for "attain inclusion."