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I'm wondering about what is the correct wording and in particular, which grammar rules are underlying your decision.

Some loci are expressed independent of the environment.

Some loci are expressed independently of the environment.

Thanks for your help!

Yamper

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As per previous comment:

They're both fine. As OED says, independent is Often used adverbially in phr. independent of (†on, †from) = Independently of, apart from, without regard to, irrespective of.

Idiomatically the simpler form is more common in your exact context.

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