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This question already has an answer here:

Can we say "guys" to a group of people, that group possibly including women?

Example sentence: I am looking forward to see you guys then!

marked as duplicate by user66974, RegDwigнt Jul 22 '15 at 9:30

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It depends on many, many factors; the country you are in, the social grouping, the formality of the occasion, the presence or otherwise of any strong feminists.

I suggest you avoid calling women guys. It's safer in all situations. Only call men 'you guys' if you have a comfortable relationship with them. If they don't know you well they may find the term too familiar.

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