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Is there Another way of saying 'Physically, mentally, psychologically, spiritually(maybe?)'

So instead of saying

Drugs are bad 'Physically, mentally, psychologically...

is there a nice phrase or a word to convey this meaning?

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The word Systemically would cover the entire body and its subsystems. In your example, you could say, "Drugs are systemically bad," or "Drugs are a systemic problem."

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    Great word :-)! In a technical context it can be paired with adverse/side effects: drugs have/cause systemic side effects or systemic adverse effects – Lucky May 21 '15 at 3:05

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