If I am expecting an answer from a question and wish to state my prediction, do I need to use quotes around a simple "yes" or "no"?
I think the answer is no. / I think the answer is "no."
That would be a yes. / That would be a "yes."
Potential end cases:
Why would he say, "No"?
The votes are in; three yeses and four nos.
The options are yes or no; not "maybe."