"I don't know the mechanics of that process enough to opine on it."
"I don't know the mechanics of that process well enough to opine on it."
Both these sentences have more than one issue. The phrase "don't know" means don't identify and can refer to a topic or people. "Mechanics" can refer to a group of people who repair items or to logistics. "Enough" or "well enough" is redundant to the initial wording "don't know"
So the sentence could be stating you don't know the individuals well enough or you don't know the process.
Consider using a better word for "know" (again know means identify) to reflect your intended meaning.
"I don't have detailed understanding" "I'm not fully proficient" "I don't recall"
Next what is the subject that you have problem with
"The process" or is it "the mechanics" (a group of people, activities, logistics, methods, implications, impacts, or engineering.)
"I don't fully understand the process logistics to opine on it." Is a concise response.
I found that words like mechanics may be used in certain industries in one country or another but are not universally interpreted the same. Thus I avoid these ambiguous word choices.