For example you would say:
Miles and miles of road
Tons and tons of food
How about when referring to the floor inside a house (given that the house is relatively big)?
[...] and [...] of plywood floor
You would say:
Acres and acres of plywood floor
Because floorage is an areal measure.
(Text rescued from potentially ephemeral comments.)
Because I couldn’t see how the asker’s two exemplars of tons of food and miles of road made any literal (read: “literal-literal” as opposed to hyperbolic) sense in the case of your run-of-the-mill single-family home, I chose the answer that seemed best-matched to those two in scope and tenor.
For rather unlike scenarios, compare these two scenarios:
Do you new give homeowners a per-square-foot pricing break for hardwood flooring installations above a certain square footage?
Wow dude, you’ve got like acres and acres of hardwood floors here hidden under your wall-to-wall carpeting!
Don’t bother stopping at the grocery store: we’ve got tons of food here.
Gosh, your driveway is like miles long!
In the US, people will often refer to large amounts of "square footage"; as in "this apartment is huge! You have a lot of open square footage".
Here are two terms for the area of a floor, in particular:
floor area, as in a large floor area
floor space, as in lots of floor space
If you really want to say plywood floor, then do so, but there is no special term for expressing the amount of floor space (area) - no more than for your tons and tons of food. You can say acres and acres of plywood floor, but there is nothing special about acre in this regard.
There are lots of different units of area, including "square" followed by any unit of length - square lightyears, for example.