I mean the physical gesture of slapping hands together. Any difference between them? Thanks.
Give me five means slapping palms above each other's heads as a a greeting, celebration gesture, or sign of joy. Sometimes one can also say Give me a five, Give me (some) skin!, Skin me!, Slip me five!, Slip me some skin!, and High five! with the same meaning.
Give me five!: Sl. Slap my hand! (as a greeting or to show joy)