Is replete used appropriately in the following sentence?
His office was like a Hollywood museum, replete with an autographed photo of Marilyn Monroe.
Or should replete only be used with categorical plurals, such as:
His office was like a Hollywood museum, replete with autographed photos of famous stars.
If a room is replete with something, then it's full or abundantly supplied with it. If there's only one thing -- in this case, a picture of Marilyn Monroe -- then the room can't be replete with it.
I'll just add to the other answers that the first sentence would be much better off with the other "plete" word, complete.
Given that replete means gorged, plentiful, stuffed. From the Latin repleo, meaning "to fill up".
I doubt a place can be replete with a single autograph.
However, I have seen it used in worse context.
The more correct sentence is the second one.
The first sentence you wrote could be understood as describing a very small office, so small that a photograph would fill it.
You can use replete with a singular noun, as in
Sensational popular fiction, replete with adultery.
