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The sensation is said to cause the mouth to pucker. From Up North Again: More of Ontario's Wilderness, from Ladybugs to the Pleiades by D Bennet and T Tiner: Chokecherries are not as dangerous as their name suggests, though they can taste harsh and astringent, causing the mouth to pucker and dry.
In Shakespeare, shall and will were not used according to the "traditional rule in Standard British English" described in your link. You can see from this Ngram that there was a big change in the rules for shall and will between 1600 and 1700, at least for first person. Since the comments say this line was composed around 1600, the grammar would presumably ...
Set one's teeth on edge –phrases.org.uk Literally, to cause an unpleasant tingling of the teeth. More generally, the expression is used to describe any feeling of unpleasant distaste. The earlier form of the phrase was 'to edge the teeth' and described the feeling of sensitivity caused by acidic tastes, like raw rhubarb. My teeth have never ...
Teacher's assistant in the US. Not sure what the equivalent would be in the UK.
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