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If you mean: can a person that is referred to by a direct object noun phrase of some verb also be referred to by a subject noun phrase of another verb, then sure. Why not? But if you mean: can a noun phrase simultaneously be the direct object of one verb and the subject of another verb, the answer is unclear. This is possible in Relational Grammar (and ...
No, "what" should never appear in these constructions. But you could use "that". 1) All that I've done is sleep. 2) After all that I've done, I still fail to ... However, it's also fine without.
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