When Petruchio invites Katherine to sit on his lap, she replies, "Asses are made to bear, and so are you." (Taming of the Shrew Act II, Scene 1.)
The denotation is clear, donkeys (Equus africanus asinus) are used as beasts of burden, and "bear" loads, and Petruchio resembles a donkey.
But is Shakespeare making a Joycean pun, 300 years avant la lettre? Something about bare bottoms?