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For example,

A: - Look! There is a centipede on the table!

B: - (interjection)!

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up vote 0 down vote accepted

A: I woke up to find a centipede in my hair. (creepy / frightening )

B: Yikes!

A: I had almost finished my salad when a centipede crawled out from under a lettuce leaf. (disgusting)

B: Ugh!

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Granted, "Yikes" isn't as dated as, for example, *"My word!", or "Golly!". But it's not exactly "current" - I find it hard to imagine anyone using it non-facetiously. – FumbleFingers Mar 15 '12 at 13:59

As the other answers have mentioned, eek (with long E as in "bleak") expresses fright, while yuck expresses disgust; I think ugh may also be suitable, depending on context: it can express both disgust and contempt.

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I see. Thank you, Jon!!! – brilliant Jan 15 '11 at 8:49
+1 for Ugh (that's what I'd say if I saw a centipede on the table)! – psmears Jan 15 '11 at 11:36

Ew works in place of yuck or ugh, especially if the speaker is a child.

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That's what immediately comes to my mind.

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Yuck! There's is a centipede on the table. Yuck will also do as eek.

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