A "pet peeve" is something minor that annoys you. What is the term for a major annoyance?
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In the sense of something that is annoying specifically to me, and not to others (like a pet peeve), I would use the words bugbear or bugaboo.
The New Zealand Oxford Dictionary (2005) gives "a cause of annoyance or anger; a bête noire" as the first definition of bugbear, and "a bogey or bugbear" as the definition of bugaboo.
OK one word request- PITA - acronym for Pain In The Ass, a major annoyance. Best word for major annoyance piss so(someone) off.
Examples: You have to delete the whole entry, make changes, and add it back in anytime you want to change anything? What a big pita!
Talk to the hand... If you have any questions --> consult my middle finger. I am so pissed off. (I am in a pissy mood)