It would be better expressed as "Stressed" vs. "Unstressed". Take the classic limerick starter, "There once was a man from Nantucket". When you speak the line, the emphasis naturally falls onto certain syllables:
there ONCE was a MAN from nanTUCKet
which looks like
da DA da da DA da da DA da
which is a nice repeating pattern.
If you try to substitute Timbuktu for Nantucket, the pattern of the emphasis is destroyed:
there ONCE was a MAN from TIMbukTU
da DA da da DA da DA da DA
As a native speaker, you should have no trouble determining that "Nantucket" fits the stress pattern called for in the standard limerick form, and "Timbuktu" does not.