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I have seen a few Q&A's with this title but none really reflects my question. I am aware both are adverbs and so forth and how they syntactically can be used equivalently, but what about connotations? Are there places where "therefore" is preferred over thus and vice versa? Are there any fine differences in usage?

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2 Answers

Therefore is used in introducing a conclusion that follows from what has been said previously.

You are drunk, and that makes you incapable of operating machinery. Therefore you shouldn't fly a plane.

Thus means in this way. For example:

He waved his arms around thus. (speaker waves arms around in demonstration)

Extending that meaning, it can be used to introduce the intended consequences of an action:

I intend to eat less, and thus lose weight.

And stretching that meaning further it can, like therefore, indicate the conclusion of an argument:

Trees are plants, and plants are living. Thus we can see that trees are living.

To me at least, in the cases where they have the same basic meaning, the effect of therefore and thus is slightly different: therefore emphasises that the conclusion is an inescapable logical consequence of what goes immediately before; thus puts more focus on the argument as a whole and the way it leads towards the conclusion.

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+1, and damn your eloquence! ;-) –  Robusto Jun 21 '11 at 13:57
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From American Heritage Dictionary of the English Language, Fourth Edition

thus

  • In this manner: Lay the pieces out thus.1
  • To a stated degree or extent; so. 2
  • Therefore; consequently: Thus3 it was necessary for me to resign.
  • For example: Few of the nation's largest cities are state capitals; thus4 neither New York nor Chicago is the seat of its state's government.

1 not same: you can not say lay the pieces out therefore.
2 not same: if I say "raise the bar thus" it is not the same as "raise the bar therefore"
3 this meaning is the same
4 not same: replacing it with therefore makes it a conclusion out of an example.

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What about the instances where 'therefore' can be used but 'thus' cannot? –  Mitch Jun 21 '11 at 13:45
    
@Mitch, on that side it is much more simple as therefore has only "1. For that reason or cause; consequently or hence." –  Unreason Jun 21 '11 at 13:50
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