From Flappers to Rappers, a book of American youth slang, records "Priscilla" as a 1920s slang word for a girl who prefers to stay home. I'm curious to know why they've chosen that name. Is there any historical figure of whom they would have used to regard a Priscilla as one who bides at the house?
The name seems to have an actual etymology that fits your question
Other names may just get associated with something due to who was given them, viz, "Sharon" being considered a low class British girl (chav)