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Is there any other word or phrase that could be used instead of "after all" in a case where it comes at the end of a sentence?

For example:

Running away was in his nature, after all.

(If you can think of a better example sentence, please let me know.)

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You could use at the end of the day, or ultimately.

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Instead of "after all", you can say "above all", "beyond everything", "most important", "most importantly", "ultimately", "when push comes to shove".

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Maybe "admittedly"?

Admittedly running away was in his nature.

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As 'admittedly' is used, this would imply that the writer was somehow 'admitting' or conceding his nature; I don't think they mean this. – Joe453 Mar 5 '11 at 14:58

You could say, though less formally, "well, running away was [italicisation quite important, but not absolutely necessary here] in his nature."

Or, in the first person: "I suppose running away was in his nature."

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