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Is it correct to use a comma after as such? For example:-

and as such, it is not possible to verify the claim.

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[on hold] even before, and, as such, ... – user51029 Sep 16 '13 at 21:37

In this case, yes. It sets off the last part of the sentence. Comma rules can be complicated, but I think this one comes under "Use a comma to set off parenthetical elements, as in "The Founders Bridge, which spans the Connecticut River, is falling down." By "parenthetical element," we mean a part of a sentence that can be removed without changing the essential meaning of that sentence."

"The Red Sox were leading the league at the end of May, but of course, they always do well in the spring."

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In the Red Sox quote, I'd tend to put a comma both before and after "of course". – Allan Sep 16 '13 at 22:00
@Allan: Perhaps, but then you really ought to omit the comma after May, which might alter the emphasis. – TimLymington Sep 16 '13 at 22:22
In this case, I would put it after but: "... at the end of May but, of course, they always do well in the spring." The parenthetical clause here is of course, not but of course, the but refers to the fact that they do well in the spring. – terdon Sep 16 '13 at 23:55
Your definition of "parenthetical element" is incorrect. Indeed, parentheticals often contain the major information in a sentence. The true definition is "a part of a sentence that can be removed without leaving an ungrammatical residue, and where the residue doesn't now carry a different sense from what it did before the deletion'. – Edwin Ashworth Oct 31 '13 at 16:15

… but it is probably the usual mis-use of the expression “as such”. (If it is such a mis-use, it should instead be “since it is” or “thus”.)

Ignoring that… I endorse putting commas before and after “as such”, to set it apart.

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